A Novel Henipavirus In Bats, Australia
Wang, Jianning; Anderson, Danielle; Valdeter, Stacey; Chen, Honglei; Walker, Som; Meehan, Brian; Williams, David; Vosloo, Wilna; Eagles, Debbie; McCullough, Sam; Wang, Linfa
2016-12-03
Conference Material
One Health EcoHealth Congress, Melbourne, 4-7 December 2016
124
Bats are the natural reservoir of a number of important viruses causing zoonotic diseases, including Ebola virus, Hendra virus (HeV), Nipah virus (NiV) and Severe Acute Respiratory Syndrome (SARS) coronavirus. Within the Henipavirus genus (family Paramyxoviridae), there are only three established species: HeV, NiV, and Cedar virus (CedPV). Two of them, HeV and NiV, are highly pathogenic, causing serious and often lethal diseases in humans and other animal species. Here, we report the detection and identification of a novel henipavirus from pteropid bats in Australia. The virus was first detected by a HeV PCR assay from spleens and kidneys of pteropid bats that died suddenly, possibly due to heat stress, in 2013 in Adelaide, South Australia, during routine diagnostic testing for HeV and Australian Bat Lyssavirus (ABLV). Virus could not be isolated in cell culture. Further analysis of partial genomic sequences demonstrated that the virus shares common genetic characteristics of henipaviruses. The virus is genetically more closely related to HeV, with 86%-88%, 78%-80%, and 70% nucleotide sequence identity to HeV, NiV and CedPV, respectively. This virus is potentially a new species of the Henipavirus genus. The biological and pathogenic characteristics of this virus remains to be determined
One Health EcoHealth
Henipavirus, Bat
Veterinary Virology
EP173003
Conference Poster
English
Wang, Jianning; Anderson, Danielle; Valdeter, Stacey; Chen, Honglei; Walker, Som; Meehan, Brian; Williams, David; Vosloo, Wilna; Eagles, Debbie; McCullough, Sam; Wang, Linfa. A Novel Henipavirus In Bats, Australia. In: One Health EcoHealth Congress; 4-7 December 2016; Melbourne. One Health EcoHealth; 2016. 124. http://hdl.handle.net/102.100.100/89293?index=1
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